Treatment of gallbladder cholesterosis in patients with type 2 diabetes mellitus using ursodeoxycholic acid

Аuthors: L.V. Zhuravlyova, T. A. Moiseyenko, Kharkiv National Medical University


Cholesterosis of gall bladder was diagnosted in 40 patients with type 2 diabetes with signs of metabolic syndrome. Treatment by ursodeoxycholic acid (orally daily before bedtime 10 mg/kg/day) during 14 days caused cholespasmolytic effect, restored function of Oddi’s and Lutkens’ sphincters, increased contractile ability of gall bladder. The purposed variant of therapy influenced the metabolic status in a positive way: it provided the restoration of albumin generating function of liver, caused antioxidant effect, improved the indexes of carbohydrate and lipid metabolism.

Keywords: type 2 diabetes, cholesterosis of gall bladder, metabolic syndrome, ursodeoxycholic acid.

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