The effectiveness of methods for perioperative pain relief in patients with burns

Authors: Sorokina E.Y., Buriak T.A., Leshev D.P., State Institution «Dnipropetrovs’k medical academy» of the Ministry of Heals of Ukraine


Predictors of the severity of pain after a thermal trauma vary depending on the phase of the burn wound healing. For the analysis of a homogeneous sample of victims with a deep burn, patients with a total burn injury area of 15.4 ± 4.2%, who underwent autodermoplasty of the skin during 14 days after the thermal trauma.

Patients were divided into two groups: first group (n = 30), which in the perioperative period was anesthetized with Sertofen (dexketoprofen trometamol 50 mg / 2 ml 2 ml 3 times a day) in the intensive care complex. The first dose of the drug was administered intraoperatively to prevent analgesia. Follow-up anesthesia with Sertofen was carried out at 50 mg / 2 ml 2 ml 3 times a day for 2-3 days postoperative period. Second group (n = 28) – in the nearest postoperative period received a narcotic analgesic (promedol 2% 1 ml), as an analgesia used analgin (metamizole sodium). All patients in the first and second observation groups underwent surgical treatment of skin burns at 12.5 ± 2.8 and 10.3 ± 2.5 days of burn disease, respectively.

It was established that in patients of first group with perioperative anesthesia with Sertofen, was observed more even decrease of pain syndrome, a tendency to lower blood levels of cortisol and stable blood glucose values.

It was concluded, that in perioperative period in patients with thermal trauma the use of dexketoprofen trometamol (Sertofen), causes effective and safe anesthesia and can be recommended in this group of patients.

Keyw ords: thermal trauma, autodermopl asty, perioperati ve anesthesia, sertofen (dexketoprofen trometamol).

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