Drug-induced liver lesions: modern approaches to treatment

Authors: N. B. Gubergrits (1), N. V. Byelyayeva (1), G. М. Lukashevich (1), L. A. Yaroshenko (1), V. S. Rachmetova (2)

(1) Donetsk National Medical University, Ukraine
(2) Medical University, Astana, Kazakhstan


The article presents a modern definition of drug-induced liver lesion, epidemiology of such lesions. The main attention is paid to a treatment. The therapeutic capacities of various hepatoprotectors have been compared, the advantages, mechanisms of action of ursodeoxycholic acid have been highlighted. The literature data on the prognosis of the drug-induced liver lesions are also presented.

Key words: drug-induced liver lesions, treatment, hepatoprotectors, ursodeoxycholic acid, advantages

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