Drug-induced liver lesions: modern approaches to treatment

Authors: N. B. Gubergrits1, N. V. Byelyayeva1, G. М. Lukashevich1, L. A. Yaroshenko1, V. S. Rachmetova2

1 Donetsk National Medical University, Ukraine
2 Medical University, Astana, Kazakhstan


Summary

The article presents a modern definition of drug-induced liver lesion, epidemiology of such lesions. The main attention is paid to a treatment. The therapeutic capacities of various hepatoprotectors have been compared, the advantages, mechanisms of action of ursodeoxycholic acid have been highlighted. The literature data on the prognosis of the drug-induced liver lesions are also presented.

Key words: drug-induced liver lesions, treatment, hepatoprotectors, ursodeoxycholic acid, advantages

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