Consequences of cholecystectomy and principles of their correction and prevention

Author: I.E. Kushnir, Ph. med. n., State Institution “National Institute of Therapy named after L.T. Minor NAMS of Ukraine”, Kharkov


In recent decades, there has been an increase in the prevalence of gallstone disease (GSD) among the adult population of the world. The number of patients with housing and communal services, according to population studies, is 10-15% and increases by 2 times every 10 years. The increase in the number of patients with HCS is due to the influence of modified risk factors, especially dietary habits with fiber deficiency in the diet and food excesses, especially the consumption of “fast” carbohydrates, high levels of obesity, a sedentary lifestyle, and the presence of concomitant metabolic diseases.

Today, different approaches are used to treat patients with HUS, in particular, the use of litholytic drugs, shock wave lithotripsy, and a surgical method. The latter method, in particular laparoscopic cholecystectomy, is considered the gold standard for the treatment of patients with GI. More than 2.5 million cholecystectomy interventions are performed annually in the world: in European countries – from 45 to 80 thousand, in the USA – more than 700 thousand, in Russia – about 500 thousand. However, unfortunately, cholecystectomy (CE) is not a radical a method that allows you to completely get rid of the symptoms of HCS. In 30.0-79.2% of patients who underwent CE for housing and communal services, various complaints remain or arise some time after surgery (abdominal discomfort, pain, dyspeptic disorders), which necessitate the appointment of drug treatment.

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