Analysis of the effectiveness of cefdinir in the treatment of acute purulent osteomyelitis in children

Authors: T.V. Marushko, Doctor of Medical Sciences, Professor, T.V. Kurilina, Doctor of Medical Sciences, Professor, S.A. Akimovich

National University of Health of Ukraine named after. P.L. Shupyk, KNP KGDKB No. 1, Kyiv

The diagnosis of HGO is established in accordance with the diagnostic criteria developed by the Society of Pediatric Infectious Diseases and the Society of Infectious Diseases of America – recommendations for the diagnosis and treatment of HGO in pediatrics (2021) [4]. In order to optimize treatment and improve prognosis, experts suggested switching antibiotic treatment from parenteral administration to oral administration of antibacterial drugs in a shorter and earlier period. The decision to switch to oral antibiotics depends on the disappearance of symptoms of fever, intoxication, improvement in physical condition and a decrease in C-reactive protein (CRP) and erythrocyte sedimentation rate (ESR).

The optimal oral drug should have a spectrum of action comparable to the parenteral one, due to which the child showed clinical and laboratory improvement [4, 8, 11].

Recently developed safety guidelines for the use of early stepwise antibiotic treatment (transition from parenteral to oral) have influenced the clinical practice of treating bone infections in our hospital.

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